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Gout is due to persistently elevated levels of uric acid in the blood. This occurs due to a combination of diet and genetic factors. At high levels, uric acid crystallizes and the crystals deposit in joints, tendons, and surrounding tissues, resulting in an attack of gout.
Gout occurs more commonly in those who regularly eat meat or seafood, drink beer, or are overweight. Diagnosis of gout may be confirmed by the presence of crystals in the joint fluid or in a deposit outside the joint. Blood uric acid levels may be normal during an attack.
Treatment with nonsteroidal anti-inflammatory drugs (NSAIDs), steroids, or colchicine improves symptoms. Once the acute attack subsides, levels of uric acid can be lowered via lifestyle changes and in those with frequent attacks, allopurinol or probenecid provides long-term prevention. Taking vitamin C and eating a diet high in low fat dairy products may be preventive.
Gout is a form of inflammatory arthritis characterized by recurrent attacks of a red, tender, hot, and swollen joint. Pain typically comes on rapidly, reaching maximal intensity in less than twelve hours. The joint at the base of the big toe is affected in about half of cases. It may also result in tophi, kidney stones, or urate nephropathy.
Gout disebabkan oleh peningkatan kadar asam urat dalam darah. Ini terjadi karena kombinasi diet dan faktor genetik. Pada tingkat tinggi, asam urat mengkristal dan endapan kristal dalam sendi, tendon, dan jaringan sekitarnya, menghasilkan serangan asam urat.
Gout lebih sering terjadi pada mereka yang secara teratur makan daging atau makanan laut, minum bir, atau kelebihan berat badan. Diagnosis asam urat dapat dikonfirmasi dengan adanya kristal dalam cairan sendi atau deposit di luar sendi. Kadar asam urat darah mungkin normal selama serangan.
Perawatan dengan obat anti-inflamasi nonsteroid (NSAID), steroid, atau colchicine meningkatkan gejala. Begitu serangan akut mereda, kadar asam urat dapat diturunkan melalui perubahan gaya hidup dan pada mereka yang sering menyerang, allopurinol atau probenesid memberikan pencegahan jangka panjang. Mengkonsumsi vitamin C dan makan diet tinggi dalam produk susu rendah lemak mungkin bersifat preventif.
Gout adalah bentuk arthritis inflamasi yang ditandai dengan serangan berulang dari sendi merah, lembut, panas, dan bengkak. Nyeri biasanya datang dengan cepat, mencapai intensitas maksimal dalam waktu kurang dari dua belas jam. Sendi di pangkal jempol kaki terkena sekitar separuh kasus. Ini juga dapat menyebabkan tophi, batu ginjal, atau nefropati urat.
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